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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2011 Nov 22;20(12):2551–2559. doi: 10.1158/1055-9965.EPI-11-0777

Table 2.

Cancer incidence rates, and rate ratios by HIV infection status

HIV+ HIV− Demographic-adjustedb Fully-adjustedb




n ratea n ratea RR (95% CI) P RR (95% CI) P
Infection-related
      Kaposi sarcoma 525 604 34 3 197.1 (139.2, 279.0) <0.001 196.0 (138.1, 278.0) <0.001
      Non-Hodgkin lymphoma 241 269 193 17 15.9 (13.2, 19.3) <0.001 15.4 (12.7, 18.7) <0.001
      Anal 86 96 18 2 60.9 (36.6, 101.4) <0.001 55.7 (33.2, 93.4) <0.001
      Hodgkin lymphoma 52 58 32 3 19.8 (12.7, 31.0) <0.001 18.7 (11.8, 29.5) <0.001
      Oral cavity/pharynx 26 29 183 16 1.9 (1.3, 2.9) 0.002 1.4 (0.9, 2.1) 0.14
      Liver 24 27 110 10 2.6 (1.7, 4.0) <0.001 1.8 (1.1, 2.8) 0.012
Infection-unrelated
      Prostate 91 112 1,398 138 0.8 (0.6, 0.9) 0.012 0.8 (0.6, 0.9) 0.012
      Lung 56 62 380 34 1.8 (1.4, 2.4) <0.001 1.2 (0.9, 1.6) 0.15
      Colorectal 35 39 459 41 0.9 (0.6, 1.3) 0.55 0.9 (0.6, 1.2) 0.34
      Melanoma 34 38 266 24 1.8 (1.3, 2.6) 0.001 1.8 (1.3, 2.6) 0.001

RR, rate ratio

a

Crude incidence rate per 100,000 person-years

b

RR comparing cancer incidence in HIV-infected individuals with HIV-uninfected individuals (reference group) from Poisson regression models. Demographic-adjusted model included terms for HIV status, age, sex, race/ethnicity, calendar period, and KP region. Fully-adjusted model also included terms for smoking, overweight, and alcohol/drug abuse.