Table II.
SMR for selected causes of death in 5 year cancer survivors
| Number of | Death due to malignant disease1 | Death due to any non-malignant disease2 |
Death due to circulatory disease |
Death due to respiratory disease |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients | Person- years |
Obs/Exp3 | SMR | 95% Cl | Obs/Exp3 | SMR | 95% CI | Obs/Exp3 | SMR | 95%CI | Obs/Exp3 | SMR | 95%CI | |
| All patients | 9245 | 147446 | 1035/56.8 | 18.2 | 17.1-19.3 | 227/116.5 | 1.9 | 1.7-2.2 | 93/50.3 | 1.9 | 1.5-2.3 | 15/6.5 | 2.3 | 1.3-3.8 |
| Age at diagnosis (yrs) | ||||||||||||||
| 0-14 | 2948 | 46412 | 242/3.6 | 67.6 | 59.4-76.4 | 36/9.6 | 3.7 | 2.6-5.2 | 7/2.6 | 2.7 | 1.1-5.5 | 2/0.5 | 4.2 | 0.5-15.0 |
| 15-19 | 1329 | 21004 | 128/5.2 | 24.5 | 20.5-29.0 | 33/12.3 | 2.7 | 1.8-3.8 | 16/4.5 | 3.5 | 2.0-5.7 | 0/0.6 | 0 | 0.0-6.0 |
| 20-34 | 4968 | 80031 | 665/48.0 | 13.9 | 12.8-14.9 | 158/94.6 | 1.7 | 1.4-2.0 | 70/43.1 | 1.6 | 1.3-2.1 | 13/5.4 | 2.4 | 1.3-4.1 |
| Sex | ||||||||||||||
| Male | 4218 | 65497.1 | 493/22.9 | 21.5 | 19.7-23.5 | 145/77.2 | 1.9 | 1.6-2.2 | 66/35.2 | 1.9 | 1.5-2.4 | 10/3.9 | 2.6 | 1.2-4.7 |
| Female | 5027 | 81949.2 | 542/33.9 | 16.0 | 14.7-17.4 | 82/39.3 | 2.1 | 1.7-2.6 | 27/15.1 | 1.8 | 1.2-2.6 | 5/2.6 | 1.9 | 0.6-4.5 |
| Follow-up time4 (yrs) | ||||||||||||||
| 0-4 | 92455 | 44150 | 554/4.4 | 124.8 | 114.7-135.0 | 27/11.7 | 2.3 | 1.5-3.4 | 3/3.6 | 0.8 | 0.2-2.4 | 4/0.6 | 6.3 | 1.7-16.1 |
| 5-9 | 82395 | 36045 | 203/5.9 | 34.2 | 29.7-39.1 | 45/15.4 | 2.9 | 2.1-3.9 | 14-5.5 | 2.6 | 1.4-4.3 | 1/0.8 | 1.3 | 0.0-7.3 |
| 10-14 | 62125 | 26672 | 82/8.0 | 10.3 | 8.2-12.7 | 41/18.9 | 2.2 | 1.6-2.9 | 15/7.4 | 2.0 | 1.1-3.3 | 2/0.9 | 2.2 | 0.3-7.8 |
| 15-19 | 44805 | 18637 | 77/10.0 | 7.7 | 6.1-9.6 | 39/21.0 | 1.9 | 1.3-2.5 | 17/8.9 | 1.9 | 1.1-3.1 | 3/1.1 | 2.9 | 0.6-8.3 |
| 20-24 | 29965 | 11845 | 57/10.8 | 5.3 | 4.0-6.9 | 34/20.0 | 1.7 | 1.2-2.4 | 20/9.3 | 2.2 | 1.3-3.3 | 4/1.1 | 3.6 | 1.0-9.1 |
| 25+ | 18065 | 10096 | 62/17.7 | 3.5 | 2.7-4.5 | 41/29.6 | 1.4 | 1.0-1.9 | 24/15.6 | 1.5 | 1.0-2.3 | 1/2.0 | 0.5 | 0.0-2.8 |
| Calendar year at diagnosis |
||||||||||||||
| 1966-1979 | 2685 | 66285.8 | 543/41.5 | 13.1 | 12.0-14.2 | 148/79.1 | 1.9 | 1.6-2.2 | 73/37.9 | 1.9 | 1.5-2.4 | 8/4.8 | 1.7 | 0.7-3.3 |
| 1980-1989 | 2946 | 50251.6 | 302/12.1 | 24.9 | 22.2-27.8 | 63/28.8 | 2.2 | 1.7-2.8 | 15/9.9 | 1.5 | 0.9-2.5 | 6/1.4 | 4.4 | 1.6-9.6 |
| 1990-1999 | 3614 | 30908.9 | 190/3.2 | 59.7 | 51.5-68.4 | 16/8.7 | 1.8 | 1.1-3.0 | 5/2.5 | 2.0 | 0.7-4.7 | 1/0.3 | 3.0 | 0.1-16.8 |
Abbreviations: SMR, standardized mortality ratio; 95% CI, 95% confidence interval; Obs, observed; Exp, expected; yrs, years
1
Death due to malignant disease = death from primary and secondary malignancies
2
Death due to any non-malignant disease = death from all diseases – death due to malignant causes
3
Obs/Exp = number of observed deaths divided by the number of expected deaths based on age-, sex-, and calendar year- specific mortality rates in the general Finnish population
4
Follow-up time starts five years after the initial diagnosis
5
Represents the number of patients alive at the beginning of each follow-up period (and thus contributing person-time to each period).