. Author manuscript; available in PMC: 2013 Jan 1.

Published in final edited form as: Pharmacogenet Genomics. 2012 Jan;22(1):32–42. doi: 10.1097/FPC.0b013e32834e1641

Table 1.

Selected Demographic and Clinical Characteristics of the Kidney Transplant Cohort

Characteristic	N = 399
Age (years)	46 ± 13
Sex:
Male	245 (61.4%)
Female	154 (38.6%)
Race:
White	303 (75.9%)
Black	84 (21.1%)
Other	12 (3%)
Weight (kg)^a	83 ± 21
Hemoglobin (g/dL)^a	12.6 ± 1.9
Albumin (g/dL)^a	4.1 ± 0.4
Time since transplant (days)^b	270 (118 – 834)
Tacrolimus C/D ratio ([ng/mL]/mg)^a	1.5 ± 0.9
Tacrolimus trough blood concentration (ng/mL)^a	7.3 ± 2.1
Total daily dose (mg/day)^a	6.5 ± 3.8

Note: All data are number (%) of subjects, mean ± standard deviation, or median (interquartile range). C/D ratio = normalized concentration-to-dose ratio.

For repeatedly measured variables, medians matched with tacrolimus C/D ratios were calculated for each patient, and then the means and SDs were estimated from all patients' median values.

For time since transplant, medians matched with tacrolimus C/D ratios were calculated for each patient, and then the median (interquartile range) was estimated from all patients' median values. The median and the interquartile range were provided to better represent the distribution of time since transplant due to high skewedness of the distribution.