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. Author manuscript; available in PMC: 2012 Dec 15.
Published in final edited form as: J Immunol. 2011 Nov 16;187(12):6491–6498. doi: 10.4049/jimmunol.1101392

Figure 1. mTi administered with OVA antigen promotes serum IgE and IgG1 elevations.

Figure 1

Mice (8/treatment group) were administered OVA protein alone, OVA + mTi, or OVA + Alum, seven days later challenged with OVA alone, and 21 days after final inoculation serum was collected from each mouse and individually assayed for total and Ag-specific Igs. Both total serum IgE and IgG1 were markedly elevated, while slight increases in total serum IgG2a (Fig 1A) were observed. Similarly, OVA-specific IgE, IgG1, and IgG2a (Fig1B) were elevated. Data are expressed as the mean and s.e. of 8 individual mice within each treatment group and all experiments were repeated twice with similar results (**p<0.01).