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. Author manuscript; available in PMC: 2012 Dec 15.
Published in final edited form as: J Immunol. 2011 Nov 16;187(12):6491–6498. doi: 10.4049/jimmunol.1101392

Figure 3. Ti triggers potent innate response in the absence of specific Ag characterized by both IL-4-dependent and IL-4-independent components.

Figure 3

Balb/c IL-4+/+ and IL-4−/− mice (5/treatment group) were inoculated ip with vehicle, Ti or Alum. Forty-eight hours later peritoneal exudate cells were collected and cell suspensions pooled from each treatment group. Pooled samples were stained for CD11b and Ly6G to detect neutrophils (A), c-kit and Siglec F to detect eosinophils (B), and F480 and CD206 to detect alternatively activated (M2) macrophages (C). This experiment was repeated two times with similar results.