Skip to main content
. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Plant J. 2011 Oct 17;68(6):1051–1060. doi: 10.1111/j.1365-313X.2011.04756.x

Figure 8. Proposed process for the repeated evolution of bi-domain terpene synthases.

Figure 8

Gene duplication and divergence of the ent-kaurene synthase (KS) required for gibberellin biosynthesis leads to KS-like (KSL) diterpene synthases, whose function can diverge. Subsequent loss of the “internal/γ” domain results in bi-domain KSLs such as DsKSL. Further functional divergence then enables reaction with other isoprenyl diphosphate substrates, presumably via intermediate states still able to catalyze the ancestral diterpene synthase reaction such as TaKSL5.