Table 1.
Baseline characteristics of patients initiating ART who were screened for TB with sputum cultures in Durban, South Africa, 2007-2008*
Characteristic | Overall N=951 |
TB Sputum Culture Positive at Enrollment N=144 |
On TB Treatment at Enrollment N=199 |
TB-Free at Enrollment N=608 |
---|---|---|---|---|
Demographic characteristics | ||||
Female (N, %) | 560 (59) | 78 (54) | 121 (61) | 361 (59) |
Age, in years, median (IQR) | 36 (31– 43) | 37 (31– 43) | 34 (30 – 41) | 37 (31– 43) |
Unemployed (N, %) | 476 (50) | 68 (47) | 111 (56) | 297 (49) |
Married (N, %) | 181 (19) | 24 (17) | 33 (17) | 124 (20) |
HIV-related characteristics | ||||
Baseline CD4 count/μl, median (IQR) | 90 (41–148) | 80 (41 – 125) | 65 (29 – 112) | 104 (49 – 160) |
WHO Stage 3 or 4 (N, %) | 627 (66) | 98 (68) | 171 (86) | 358 (59) |
History of OI (N, %) | 497 (52) | 69 (48) | 113 (57) | 315 (52) |
Other baseline clinical characteristics | ||||
Prior history of TB (N, %)† | 245 (26) | 28 (19) | 47 (24) | 170 (28) |
Hospitalized in last 5 years (N, %) | 251 (26) | 26 (18) | 68 (34) | 157 (26) |
Household member with history of TB (N, %) |
229 (24) | 33 (23) | 51 (26) | 145 (24) |
Baseline hemoglobin, median (IQR) | 11.1 (9.5-12.6) | 10.2 (8.5 – 11.8) | 10.3 (9.2 – 11.8) | 11.6 (10.0 – 13.0) |
Baseline weight (kg), median (IQR) | 61 ( 53 – 72) | 57 ( 51 – 65) | 60 ( 52 – 66) | 63 ( 55 – 75) |
Current or past smoker (N, %) | 264 (28) | 47 (33) | 54 (27 ) | 163 (27) |
Excludes 84 patients who were screened but who were taking ART at study entry
Prior history indicates self-reported TB episode that precedes either current or new episode
TB: Tuberculosis; IQR: Inter-quartile range; WHO: World Health Organization; OI: Opportunistic infection; ART: antiretroviral therapy; kg: kilogram