Table 2.
Sample Size, Breast Cancer Cases, and Person-years of Follow-up by Birth Cohort for Female Cleft Cases, Mothers and Sisters of Cleft Cases and Background Population
| Birth Cohorts |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| 1911–1936 | 1935–1940 | 1941–1945 | 1946–1950 | 1951–1955 | 1956–1960 | 1961–1965 | 1966–1970 | 1971–1975 | |
| Cleft Cases | 0 | 143(11)* | 198(9) | 210(11) | 225(11) | 241(3) | 256(1) | 268(1) | 268(2) |
| 9185 | 11991 | 11742 | 11314 | 10709 | 10303 | 9528 | 8123 | ||
| Reference | 0 | 6981(407) | 8858(482) | 9485(392) | 8600(219) | 8429(127) | 9293(76) | 8977(30) | 8711(7) |
| 454627 | 535171 | 530003 | 436100 | 380051 | 371055 | 314952 | 262326 | ||
| Mothers of Cleft Cases | 1023(59) | 577(39) | 675(27) | 682(26) | 631(13) | 623(6) | 624(3) | 476(1) | 281(0) |
| 74688 | 37395 | 40872 | 38419 | 32454 | 28642 | 25446 | 17285 | 8947 | |
| Reference | 27073(1765) | 14589(880) | 17619(883) | 17739(689) | 15117(349) | 14790(199) | 15991(81) | 12862(42) | 6879(2) |
| 2044829 | 951551 | 1068989 | 995981 | 772550 | 675300 | 647900 | 463353 | 215788 | |
| Sisters of Cleft Cases | 0 | 0 | 4(0) | 11(0) | 113(6) | 382(4) | 612(4) | 628(0) | 593(0) |
| 246 | 624 | 5540 | 17046 | 24250 | 22354 | 18093 | |||
| Reference | 0 | 0 | 110(4) | 315(9) | 3087(82) | 10790(153) | 16364(96) | 15492(48) | 14633(14) |
| 6692 | 17612 | 151707 | 480697 | 652221 | 545239 | 443225 | |||
*
Number of subjects (# of cancers) – person years of follow-up