Table 1.

Liver Tumors in Trp53^KO and Trp53^KO;Tgfbr2^KO Mice

Genotype	Total # of Mice	Median Survival of Entire Cohort (weeks)	Median Survival of Mice with Tumors (weeks)	# of Mice with Liver Tumors	% of Mice with Liver Tumors	Liver/Body Weight Ratio of Entire Cohort	Liver/Body Weight Ratio of Mice with Tumors
Trp53KO	29	46.6	22.7€	12§	41	0.096†	0.132‡
Trp53KO;Tgfbr2KO	36	64.0	71.6€	6§	17	0.054†	0.063‡
Tgfbr2KO	19	65.3	N/A	0	0	0.050	N/A
Control	14	65.0	N/A	0	0	0.050	N/A

^€P = 0.0017, Trp53^KO vs. Trp53^KO;Tgfbr2^KO mice, Mann-Whitney test

^§P = 0.0265, Trp53^KO (12/29) vs. Trp53^KO;Tgfbr2^KO (6/36) mice, Fisher’s exact test

^†P = 0.0002, Trp53^KO vs. Trp53^KO;Tgfbr2^KO mice, Mann-Whitney test

^‡P = 0.0149, Trp53^KO vs. Trp53^KO;Tgfbr2^KO mice, Mann-Whitney test