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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Eur J Neurosci. 2011 Nov 29;34(12):1997–2006. doi: 10.1111/j.1460-9568.2011.07914.x

Figure 5.

Figure 5

Discriminative stimuli differentially evoke phasic dopamine signaling across striatal subregions. Average dopamine (black line) ± SEM (gray vertical bars) to predictive cues in striatal subregions during the discriminative stimulus test. Top: A cue predictive of reward (DS+) selectively evokes phasic dopamine release in the Core (B) and DMS (C) but not the Shell (A) or DLS (D). Insets: Average dopamine signal for each rat during both Baseline and Cue epochs. Note that in the Core (B), the scale for the ordinate is 2 nA, twice that of the other striatal regions. * P < 0.05 for Baseline versus DS+ epoch. Bottom: A cue predictive of no reward (DS-) fails to alter phasic dopamine signaling in all striatal subregions. Insets: Average dopamine concentration for each rat during both Baseline and Cue epochs.