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. Author manuscript; available in PMC: 2012 Dec 7.
Published in final edited form as: Cell Metab. 2011 Nov 10;14(6):758–767. doi: 10.1016/j.cmet.2011.10.007

Figure 6. Creb K136Q prevents lipid abnormalities in WTD-fed SirBACO mice.

Figure 6

(A–C) Hepatic lipid content characterized by Oil Red-O staining (A), TG (B) and cholesterol measurements (C) (n=7–9 each).

(D) Liver weight (n=7–9).

(E–G) Plasma TG (D), glucose (E) and insulin (F) after 24-hour fasting (Fasted) followed by 4-hour re-feeding (Refed) (n=7–9).

(H–J) Body weight change (H) and composition, with lean (I) and fat mass (J) n=7–9) during WTD feeding. In all experiments **=P<0.01, *=P<0.05. Open bar: Ad-Creb in WT mice; black bar: Ad-Creb in SirBACO mice; blue bar: Ad-K136Q in WT mice; red bar: Ad-K136Q in SirBACO mice. Data are expressed as means ± SEM.