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. Author manuscript; available in PMC: 2012 Dec 6.
Published in final edited form as: Curr Biol. 2011 Nov 23;21(23):1979–1987. doi: 10.1016/j.cub.2011.11.002

Figure 3.

Figure 3

Role of WNK1 in activation of TRPC6 by Gq-coupled receptor. (A) Whole-cell inward TRPC6 current density in response to CCh with anti-WNK1 Ab, GDPβS or control buffer applied via patch pipettes. *, p < 0.01, WNK1-Ab vs control. (B) Whole-cell CCh-induced TRPC6 currents were recorded in the presence of control buffer or WNK11–491 (3 nM), a concentration that does not appreciably stimulate TRPC6 by itself. *, p < 0.01, WNK1 vs buffer. (see also Figure S3).

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