Table 1.
SNP | Gene | Chr | Base-pair Position |
MAF cases |
MAF controls |
P | Odds Ratio |
95% Confidence Interval |
---|---|---|---|---|---|---|---|---|
rs4906902 | GABRB3 | 15 | 24570861 | 0.14 | 0.22 | 3.6E-06 | 0.46 | 0.33 – 0.64 |
rs8192619 | TAAR1 | 6 | 133008041 | 0.08 | 0.03 | 1.1E-05 | 3.76 | 2.08 – 6.78 |
rs7911 | GBP1 | 1 | 89290708 | 0.41 | 0.32 | 1.1E-04 | 1.66 | 1.28 – 2.14 |
rs4234955 | NPY1R | 4 | 164479726 | 0.23 | 0.29 | 0.001 | 0.64 | 0.49 – 0.84 |
rs7537937 | GBP2 | 1 | 89355278 | 0.36 | 0.30 | 0.001 | 1.53 | 1.18 – 1.98 |
rs10754261 | GBP2 | 1 | 89363670 | 0.36 | 0.30 | 0.001 | 1.53 | 1.18 – 1.98 |
rs4453447 | GABRB3 | 15 | 24554565 | 0.11 | 0.15 | 0.002 | 0.55 | 0.38 – 0.80 |
rs694066 | GAL | 11 | 68209561 | 0.06 | 0.09 | 0.002 | 0.47 | 0.30 – 0.76 |
rs10799897 | RGS4 | 1 | 161309712 | 0.46 | 0.41 | 0.002 | 1.47 | 1.15 – 1.89 |
rs757228 | GPX4 | 19 | 1052992 | 0.44 | 0.48 | 0.002 | 0.69 | 0.54 – 0.88 |
rs1329119 | GBP2 | 1 | 89346614 | 0.34 | 0.28 | 0.003 | 1.48 | 1.14 – 1.92 |
rs4656093 | GBP2 | 1 | 89344563 | 0.34 | 0.28 | 0.004 | 1.47 | 1.14 – 1.91 |
rs4656095 | GBP2 | 1 | 89351396 | 0.34 | 0.28 | 0.004 | 1.47 | 1.14– 1.91 |
rs7154455 | ESR2 | 14 | 63806413 | 0.33 | 0.30 | 0.005 | 1.43 | 1.12 – 1.84 |
rs2302109 | GPX4 | 19 | 1061829 | 0.47 | 0.50 | 0.005 | 0.71 | 0.56 – 0.90 |
rs1256030 | ESR2 | 14 | 63816923 | 0.45 | 0.49 | 0.007 | 0.73 | 0.59 – 0.92 |
rs6454674 | CNR1 | 6 | 88929649 | 0.29 | 0.33 | 0.007 | 0.69 | 0.53 – 0.91 |
rs3783736 | ESR2 | 14 | 63821125 | 0.42 | 0.39 | 0.007 | 1.38 | 1.09 – 1.74 |
rs1271572 | ESR2 | 14 | 63831670 | 0.45 | 0.49 | 0.007 | 0.73 | 0.58 – 0.92 |
rs642544 | GRIA4 | 11 | 105242230 | 0.38 | 0.43 | 0.009 | 0.72 | 0.57 – 0.92 |
Association results for top 20 ranked SNPs from the primary case/control study used to select genes for replication (SNPs that failed quality checks and ancestry-informative markers have been removed).
Abbreviations: Chr (chromosome), MAF cases (minor allele frequency in cases), MAF controls (minor allele frequency in controls).