Table 1.
Injury | Definition | Per cent (N samples) |
---|---|---|
Steatosis | ||
Grade 0 | 0% | 24.4% (57) |
1 | >0–5% | 30.8% (72) |
2 | >5–33% | 26.9% (63) |
3 | >33–66% | 12.0% (28) |
4 | >66% | 6.0% (14) |
Sinusoidal injury | ||
Grade 0 | Nil | 70.5% (165) |
1 | up to 1/3 lobular involvement | 14.1% (33) |
2 | >1/3–2/3 lobular involvement | 6.8% (16) |
3 | >2/3 to complete lobular involvement | 8.6% (20) |
Steatohepatitis | ||
Presence | steatosis > 5%, NAFLD activity score* > 2 | 4.3% (10) |
NAFLD activity score = sum of scores for: Mallory bodies + lobular inflammation + hepatocyte ballooning + perisinusoidal fibrosis (each factor scored 0 = absent, 1 = focal involvement of some lobules, 2 = focal involvement of most lobules, 3 = focal involvement of most or all, with diffuse involvement of some or most).23