Table 4.
Cohort | Injury | Number of samples | Ratio target: GAPDH (range) | Standard deviation | P-value | |
---|---|---|---|---|---|---|
DPD | All samples | Steatosis | 21 | 5.733 (0.124–20.633)* | 6.705 | <0.02 |
No steatosis | 71 | 2.677 (0.102–21.900) | 4.300 | |||
Chemo only | Steatosis | 18 | 3.662 (0.124–15.842) | 4.909 | <1.0 | |
No steatosis | 38 | 3.005 (0.102–21.900) | 4.524 | |||
ERCC2 | All samples | Sinusoidal injury | 6 | 14.522 (0.178–65.662) | 28.566 | <0.01 |
No SI | 37 | 4.603 (0.103–67.905) | 11.442 | |||
Chemo only | Sinusoidal injury | 3 | 34.130 (2.707–65.662) | 44.438 | <0.001 | |
No SI | 25 | 4.357 (0.103–67.905) | 13.420 |
NB: higher ratio target: GAPDH represents lower expression of that target.