Table 2.
Comparisons of clinical parameters to determine risk factors of virological failure among 788 HIV-infected patients
Variables | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
Odds Ratio (95% CI) | P-value | Odds Ratio (95%CI) | P-value | |
Male vs. female | 0.95 (0.65-1.69) | 0.847 | - | - |
Age < 40 vs. ≥ 40 years | 2.06 (1.23-3.46) | 0.006 | 2.28 (1.22-4.25) | 0.040 |
Heterosexual vs. non-heterosexual transmission | 0.49 (0.20-1.23) | 0.125 | ||
Urban vs. rural area | 1.18 (0.66-2.10) | 0.581 | - | - |
No health insurance vs. had health insurance | 0.77 (0.23-2.57) | 0.671 | ||
OIs before cART vs. no OIs before cART | 0.84 (0.53-1.36) | 0.488 | - | - |
Baseline CD4 cell count < 100 vs. ≥ 100 cells/mm3 | 1.56 (0.91-2.69) | 0.106 | - | - |
Positive HCV antibody vs. negative HCV antibody | 0.93 (0.35-2.44) | 0.887 | - | - |
Positive HBs Ag vs. negative HBs antigen | 1.25 (0.54-2.89) | 0.603 | - | - |
Adherence < 95% vs. ≥ 95% | 87.24 (32.29-235.72) | < 0.0001 | 86.49 (31.19-239.80) | < 0.001 |
Abbreviations: OI, opportunistic infection; cART, combination antiretroviral therapy; HCV, hepatitis C virus; HBs Ag, hepatitis B surface antigen