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Data from 7 families with 5α-reductase type 2 deficiency, 5 families with PAIS, and 39 isolated undetermined cases.
| 5α-reductase type 2 deficiency | PAIS | Undetermined | P value* | ||
|---|---|---|---|---|---|
| Parental consanguinity | + | 5 | 2 | 2 | P = 0.00005 |
| − | 2 | 3 | 37 | ||
| Familial recurrence | + | 3 | 5 | 13 | P = 0.02 |
| − | 4 | 0 | 26 | ||
| Ambiguous genitalia Sinnecker et al. [9] | 2 | 1 | 3 | 29 | P = 0.0004 |
| 3 | 7 | 2 | 10 | ||
| 4 | 1 | 5 | 0 | ||
| Ambiguous genitalia Ahmed et al. [10] | <3.5 | 6 | 7 | 4 | P = 0.00003 |
| ≥3.5 | 3 | 3 | 35 |
*Chi-square test.
