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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: Vaccine. 2009 May 27;27(32):4309–4319. doi: 10.1016/j.vaccine.2009.05.011

Fig. 1.

Fig. 1

Schematic representation of SIN/CO92, SIN/SIN/McM, and SIN/EEE/McM chimeras. The SIN/CO92 chimera (A) includes the nonstructural protein gene regions of SIN strain AR339 and the structural protein gene regions of WEEV strain CO92-1356. The SIN/SIN/McM chimera (B) includes the nonstructural protein gene regions and the amino-terminal domain of the capsid of SINV strain AR339 and the carboxy-terminal domain of the capsid and envelope glycoproteins of WEEV strain McMillan. The SIN/EEE/McM chimera (C) includes the nonstructural protein gene regions of SINV strain AR339, the amino-terminal domain of the capsid of EEEV strain 436087, and the carboxy-terminal domain of the capsid and envelope glycoproteins of WEEV strain McMillan.