Fig. 4.

Replication of parental and chimeric SIN/SIN/McM and SIN/EEE/McM strains in (A) mammalian Vero and (B) mosquito C710 cells. Cells were infected in triplicate at a MOI of 1 PFU/cell for 1 h, washed three times with PBS, and then, viral titers in the culture medium were determined by plaque assay on Vero cells at selected times after infection. Bars indicate standard deviations.