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Neutralizing antibody titers in female 10-week-old NIH Swiss mice 4 weeks after immunization with either SIN/SIN/McM or SIN/EEE/McM chimera
| Vaccine | Vaccine dose (log10 PFU/mouse) | Mean 80% PRNT titer ± SD | No. of PRNT seropositive |
|---|---|---|---|
| SIN/SIN/McM | 4.8 | 600 ± 113 | 8/8* |
| 5.8 | 604 ± 106 | 10/10 | |
| SIN/EEE/McM | 4.6 | 420 ± 252 | 8/10 |
| 5.6 | 416 ± 215 | 10/10 |
two mice died before testing of sera for antibodies
