TABLE 4.
Predicted obligatory cysteine oxidation relative to measured cysteine oxidation1
| Protein flux2 | SAA/protein3 | SAA flux | SAA oxidation4 | Predicted cysteine oxidation5 | Measured cysteine oxidation | |
| g · kg · d−1 | mg/g | mg · kg · d−1 | mg · kg · d−1 | mg · kg · d−1 | mg · kg · d−1 | |
| Malnourished | ||||||
| Nonedematous | 7.8 | 35 | 275 | 27.5 | 16.5 | 15.1 |
| Edematous | 5.2 | 35 | 182 | 18.2 | 10.9 | 4.9 |
| Catch-up growth | ||||||
| Nonedematous | 9.8 | 35 | 343 | 34.3 | 20.6 | 27.3 |
| Edematous | 11.1 | 35 | 388 | 38.8 | 23.3 | 10.2 |
1
Predicted cysteine oxidation was calculated by using the approach of Young et al (17); measured oxidation values are from the present study. SAA, sulfur amino acid (cysteine and methionine).
2
Fasting state protein flux in early-childhood severe acute malnutrition (16), assuming that leucine content of 1 g body protein equals 75 mg (18), and during catch-up growth (19).
3
SAA composition of whole-body protein (18).
4
Assumes that endogenous amino acids are recycled with 90% efficiency (17).
5
Assumes that cysteine oxidation is 1.5 times that of methionine oxidation while receiving a sulfur amino acid–free diet (17).