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. Author manuscript; available in PMC: 2012 Apr 27.
Published in final edited form as: N Engl J Med. 2011 Oct 27;365(17):1567–1575. doi: 10.1056/NEJMoa1106955

Figure 1. Lung-Tissue Samples Matched with CT Images.

Figure 1

Panel A shows a frozen lung slice from a patient with severe centrilobular emphysema, and Panel B shows the same lung slice after samples were removed for analysis. Panel C shows the matching slice from the multidetector CT scan of the intact lung specimen, with the location of samples indicated by circles. Panel D shows a single control lung sample after it was processed for microCT. Panel E shows a microCT image of a control lung at a resolution of 16.24 μm, with a terminal bronchiole (indicated by the white line) at the point at which it branches into respiratory bronchioles. Panel F shows the same terminal bronchiole reoriented to show the cross section of the airway (arrow) at the plane of the section indicated by the line in Panel E.