Table 4.
Oncogenes and tumor suppressors significantly affected in lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC)
| Name | Description | Fold-change | p-value |
|---|---|---|---|
| Adenocarcinoma | |||
| FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | -2.02 | 9.18 × 10-4 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -2.14 | 4.87 × 10-4 |
| Squamous cell carcinoma | |||
| ECT2 | Epithelial cell transforming sequence 2 oncogene | 3.59 | 2.55 × 10-8 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 2.66 | 4.00 × 10-7 |
| JUN | jun oncogene | -2.30 | 7.39 × 10-9 |
| FOS | v-fos FBJ murine osteosarcoma viral oncogene homolog | -2.80 | 7.18 × 10-7 |
| ROS1 | c-ros oncogene 1 , receptor tyrosine kinase | -2.97 | 8.79 × 10-9 |
| CXCL2 | Chemokine (C-X-C motif) ligand 2 | -3.65 | 2.45 × 10-8 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -4.65 | 1.60 × 10-9 |
| DLG1 | Discs, large homolog 1 (Drosophila) | 2.41 | 3.46 × 10-5 |
| DLGAP5 | Discs, large (Drosophila) homolog-associated protein 5 | 2.35 | 4.22 × 10-7 |
| TGFBR2 | Transforming growth factor, beta receptor II (70/80 kDa) | -2.09 | 1.85 × 10-11 |