Table 4. Clinical and laboratory data of patients with different types of fusion BCR-ABL transcripts and MDR1 expression.
| Parameter | MDR1(+) patients | P | MDR1(−) patients | P | ||
|---|---|---|---|---|---|---|
| b3a2 [n=25] | b2a2 [n=23] | b3a2[n=28] | b2a2[n=21] | |||
| Age: mean±SD [years] | 53.0±15.2 | 51.6±16.0 | NS | 49.3±12.1 | 47.9±13.6 | NS |
| Patients | ||||||
| >55 years [n=] | 12 [48%] | 12 [52%] | NS | 7 [25%] | 5 [24%] | NS |
| <55 years [n=] | 13 [52%] | 11 [48%] | 21 [75%] | 16 [76%] | ||
| Gender | ||||||
| Males [n=] | 11 [44%] | 16 [70%] | NS | 17 [61%] | 15 [71%] | NS |
| Females [n=] | 14 [56%] | 7 [30%] | 11 [39%] | 6 [29%] | ||
| WBC: | 85.4±61.2 | 130±93.9 | 0.004 | 150.8±86.6 | 134.6±109.5 | NS |
| mean±SD [×109/L] | ||||||
| Platelets: | 908.7±470.1 | 472.9±356.1 | 0.006 | 727.3±434.0 | 403.8±189.1 | NS |
| mean±SD[×109/L] | ||||||
| Hemoglobin: | 123.5±18.6 | 103.1±46.2 | NS | 112.7±19.4 | 112.1±15.6 | NS |
| mean±SD [g/L] | ||||||