Table 2.
Mean ± standard deviation of performance on measures of speech production and cognition in patients with frontotemporal lobar degeneration and controls1,2
| PNFA | SemD | SOC/EXEC | Controls | |
|---|---|---|---|---|
| SPEECH OUTPUT | ||||
| Fluency (words/minute) | 46.9 ± 21.7 *+ | 88.0 ± 32.3 * | 89.2 ± 48.2 * | 142.1 ± 23.8 |
| Speech errors/utterance | 0.35 ± 0.34 *+ ° | 0.04 ± 0.05 | 0.02 ± 0.04 | 0.002 ± 0.005 |
| Total words | 329 ± 223 * | 612 ± 414 | 544 ± 209 | 585 ± 109 |
| Duration (seconds) | 436 ± 210 | 434 ± 223 | 442 ± 254 | 255 ± 76 |
|
| ||||
| GRAMMAR, STRUCTURE, CONTENT PER UTTERANCE | ||||
| Mean length of utterance (words) | 7.3 ± 2.5 * | 8.3 ± 2.3 | 9.4 ± 2.3 | 10.4 ± 1.8 |
| Complex structures | 0.16 ± 0.11 * | 0.23 ± 0.13 | 0.23 ± 0.13 | 0.36 ± 0.11 |
| Verbs | 1.11 ± 0.43 * | 1.41 ± 0.33 | 1.43 ± 0.29 | 1.69 ± 0.22 |
| Nouns | 1.46 ± 0.48 * | 1.25 ± 0.54 * ° | 1.93 ± 0.43 | 2.09 ± 0.41 |
| Existential subjects | .044 ± .037 + | .128 ± .081 * | .116 ± .125 | .046 ± .024 |
|
| ||||
| NEUROPSYCHOLOGICAL MEASURES: COMPREHENSION, EXECUTIVE, SEMANTIC | ||||
| Sentence comprehension (max = 48) | 32.6 ± 8.3 * (7) | 26.3 ± 4.8 * (6) | 35.9 ± 8.7 (7) | 46.0 ± 1.2 (5) |
| Reverse digit span | 3.0 ± 1.7 * (11) | 2.9 ± 1.9 (10) | 3.8 ± 1.4 (8) | 5.6 ± 1.3 (5) |
| Stroop time (max = 300 s) | 252 ± 47 * (10) | 285 ± 37 * (6) | 189 ± 96 (6) | 84 ± 14 (5) |
| Animal fluency (#/min) | 10.3 ± 4.9 * (11) | 9.8 ± 6.6 * (10) | 13.4 ± 6.7 * (8) | 25.3 ± 5.4 (6) |
NOTES
1, *
differs from Controls, p<.01
+
differs from SemD, p<.01
°
differs from SOC/EXEC, p<.01.
2
Numbers in parentheses for the neuropsychological tests indicate the numbers of participants who performed these tests.