Table 1.
Variable | Total study population (n=456) | No MI before TIA (n=388) | No incident MI after TIA (n= 344) | Incident MI after TIA (n=44) | Hazard Ratio (95% CI) | P-value |
---|---|---|---|---|---|---|
Age at index TIA (mean ± SD; years) | 72 ± 14 | 71±14 | 71±15 | 72±12 | 1.42 (1.10–1.83)* | 0.007 |
Male (%) | 43 | 41 | 40 | 55 | 1.53 (0.84–2.77) | 0.16 |
Hypertension (%) | 64 | 62 | 61 | 70 | 2.02 (1.04–3.92) | 0.04 |
Smoking (%) | 55 | 55 | 54 | 57 | 0.91 (0.50–1.66) | 0.75 |
Diabetes (%) | 13 | 11 | 11 | 9 | 1.12 (0.40–3.14) | 0.83 |
Lipid lowering treatment (%) | 5 | 5 | 4 | 11 | 2.42 (0.95–6.16) | 0.06 |
Antithrombotic treatment (%) | 75 | 84 | 83 | 88 | 1.25 (0.49–3.18) | 0.64 |
TIA etiology subtype (%) | ||||||
Large artery atherosclerosis | 20 | 19 | 18 | 27 | 1.51 (0.78–2.93) | 0.22 |
Cardioembolic | 15 | 13 | 14 | 9 | 0.74 (0.26–2.08) | 0.57 |
Lacunar | 5 | 6 | 5 | 9 | 1.62 (0.58–4.54) | 0.36 |
Unknown | 55 | 57 | 58 | 48 | 0.67 (0.37–1.22) | 0.19 |
Other | 4 | 5 | 5 | 7 | 1.44 (0.45–4.68) | 0.54 |
Hazard Ratio is per 10 years
Abbreviations: MI: myocardial infarction; TIA: transient ischemic attack