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(A) Theophylline dose-dependent inhibition of SEAP expression of the theo-TetR intramer (red) relative to the inactivated TetR intramer variant (blue) in HEK293-T cells. (B) Theophylline and doxycycline cross-titration of the theo-TetR intramer in HEK293-T cells. Intersection points of the grid represent SEAP expression levels measured in duplicates.
