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Sequence conservation in the interface between EF-Tu and aa-tRNA. Percent amino acid identity among bacterial EF-Tu sequences mapped onto the structure of yeast Phe-tRNAPhe bound to T. aquaticus EF-Tu (11). Sequence conservation on tRNA using a bits scale (56) is similarly mapped. (A) Global structure of the ternary complex. (B) The esterified amino acid binding pocket with esterified phenylalanine is shown in grey. (C) The T-stem recognition sites.
