Table 1.
Five anti-RNAP III positive cases that were not classified as SSc at their initial visit
| 1 | 2 | 3 | 4 | 5 | |||
|---|---|---|---|---|---|---|---|
| Initial | f/u | Initial | f/u | ||||
| Diagnosis | Vasculitis? | SSc | Poly -arthritis |
SSc | Sine SSc? | ILD | Sjögren's syndrome |
| Race/gender | WF | Mixed F | WF | WF | WF | ||
| Anti-RNAP III ELISA (u) |
16 | NA | 99 | 127 | 8 | 15 to 47 |
42 |
| Proximal scleroderma | N | Y < 10 mo |
N | Y 3 mo |
N | N | N |
| Sclerodactyly | N | Y < 10 mo |
N | Y 2 mo |
N | N | N |
| Pitting scar | N | N | N | N | N | N | N |
| ILD | N | N | N | N | N | Y | N |
| Raynaud's phenomenon | N | ? | N | Y 6 mo |
Y For 10 y |
N | N |
| Other | Renal crisis 10 mo |
Flex.cont PH |
ARF (TMA), DCM | ||||
ARF, acute renal failure; DCM, dilated cardiomyopathy; W, white; F, female; Flex cont, flexion contracture; f/u, follow up; ILD, interstitial lung disease; N, no; NA, not available; PH, pulmonary hypertension; SSc, systemic sclerosis, scleroderma; TMA, thrombotic microangiopathy; Y, yes