Table 1.

Possible signs of sepsis (adapted from [7])

Parameters	Signs
General	Fever, chills
Inflammatory	Altered white blood cell count, increased serum concentrations of C-reactive protein or procalcitonin
Coagulopathy	Increased D-dimers, low protein C, increased prothrombin time/activated partial thromboplastin time
Hemodynamic	Tachycardia, increased cardiac output, low systemic vascular resistance, low oxygen extraction ratio
Metabolic	Increased insulin requirements
Tissue perfusion	Altered skin perfusion, reduced urine output
Organ dysfunction	Increased urea and creatinine, low platelet count or other coagulation abnormalities, hyperbilirubinemia