Table 4.
Outcome measures: percentage change or improvement, baseline to 72 hours
| Outcome measure | Control | Treatment | P value |
|---|---|---|---|
| ScvO2 * | 32.7 | 44.9 | 0.001 |
| Lactate* | 43.5 | 61.0 | 0.02 |
| Base deficit* | 42.7 | 77.5 | 0.001 |
| pH* | 5.4 | 12.3 | 0.001 |
| APACHE II* | 24.5 | 40.2 | 0.002 |
| Mortality in hospital | 46.5 | 30.5 | 0.009 |
| Mortality at 28 days | 49.2 | 33.3 | 0.01 |
| Mortality at 60 days | 56.9 | 44.3 | 0.03 |
| Length of hospital stay† | - | 20.7 | 0.04 |
APACHE II, Acute Physiology and Chronic Health Evaluation; ScvO2, central venous oxygen saturation. * Baseline to 72 hours. †Surviving to hospital discharge.