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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Math Biosci. 2010 Aug 11;229(2):135–148. doi: 10.1016/j.mbs.2010.08.003

Figure 10.

Figure 10

Implication of administration of IL-1 receptor antagonist by decreasing concentration of (M) through increasing the degradation rate constant. Increase kout,M by 20% and 40% respectively from the 5th hour. The larger the degradation rate of (M), the lower the response will be for (M) the intermediate proinflammatory response, (L) the proinflammatory response, (A) the anti-inflammatory, and (D) the anabolism. All the responses, including the anabolism, returned to baseline after a period of time.