Table 1.

Estimated values of the parameters based on self- limited response data

Index	Parameter	Value	min	max	5%quantile	95%quantile
1	TRon	1
2	tTR	0.3
3	xTR	0.5
4	ksyn	0.0178	0.0001	0.1907	0.0009	0.0237
5	kdeg	0.0178
6	k1	2.9835	2.6402	3.1860	2.7806	3.1419
7	k2	0.0448
8	kin, mRNA,TNFR1	0.0892	0.0025	0.1962	0.0771	0.0955
9	kout, mRNA, TNFR1	0.2447
10	kTNFR1,E	1.7439	1.6189	1.8659	1.6463	1.8363
11	k3	4.9924	4.6696	5.2970	4.7187	5.2616
12	k4	2
13	kNFκB,1	16.2767	15.3150	17.2588	15.3907	17.1419
14	kNFκB,2	1.0124	0.2565	1.2480	0.9484	1.1187
15	kin,IκBα	0.5019	0.3686	2.7546	0.4370	0.7228
16	kIκBα,1	13.2824	12.4863	14.0660	12.5927	14.0074
17	kout,IκBα	0.5019
18	kI,1	1.4
19	kI,2	1.48
20	kin,E	1.3944	1.1954	1.6907	1.2758	1.4831
21	kE,NFκB	7.2374	6.7439	7.6585	6.8332	7.5813
22	kout,E	1.3944
23	τ1	1.2208	1.1429	2.2262	1.1562	1.2986
24	kin,M	0.1895	0.14406	0.5711	0.16058	0.2033
25	kout,M	0.8693
26	kM, M1	3.5872	3.3779	3.8097	3.3999	3.7865
27	γ1	1.5505	1.3912	2.2236	1.4310	1.8318
28	τ2	9.7784	9.1848	10.3504	9.2556	10.2919
29	kin,L	0.1679	0.1386	0.2758	0.1489	0.2210
30	kout,L	0.2524
31	kL, M2	0.5193	0.2501	0.6325	0.3277	0.5728
32	γ2	3.9989	3.5282	4.2362	3.7943	4.1953
33	kin,A	0.0021	0.0007	0.0069	0.0009	0.0027
34	kout,A	0.0452
35	kA,L	20.5386	19.3222	21.7660	19.4349	21.6616
36	γ3	1.5684	1.4025	2.2521	1.4370	2.0230
37	kin,D	3.3369	3.1351	3.5332	3.1592	3.5165
38	kout,D	0.2709
39	kD,L	1.1756	1.0955	1.2469	1.1103	1.2359
40	kD,A	4.6662	4.3858	4.9442	4.4139	4.9180