Table 2.

Relative sequence specificities of matrixins influenced by the P1' position

	Relative rate of hydrolysis
P4–P3–P2–P1 ~ P1'-P2'-P3'-P4'	MMP-1	MMP-2	MMP-3
Gly-Pro-Gln-Gly ~ Ile-Ala-Gly-Gln	100	100	100
Gly-Pro-Gln-Gly ~ Leu-Ala-Gly-Gln	130	88	110
Gly-Pro-Gln-Gly ~ Val-Ala-Gly-Gln	9.1	30	53
Gly-Pro-Gln-Gly ~ Ser-Ala-Gly-Gln	5.9	15	45
Gly-Pro-Gln-Gly ~ Phe-Ala-Gly-Gln	20	55	140
Gly-Pro-Gln-Gly ~ Met-Ala-Gly-Gln	110	230	60
Gly-Pro-Gln-Gly ~ Gln-Ala-Gly-Gln	28	34	38
Gly-Pro-Gln-Gly ~ Glu-Ala-Gly-Gln	<0.5	<0.5	<0.002
Gly-Pro-Gln-Gly ~ Arg-Ala-Gly-Gln	<0.5	<0.5	<4.9

MMP, matrix metalloproteinase.