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(A, B, C, D) Vulnerable window for WT and N588K along the 1D strand for different EPI∶MIDDLE∶ENDO IKr density ratios; (A) 1.0∶1∶1 (B) 1.5∶1∶1 (C) 1.6∶1∶1 (D) 1.7∶1∶1. (E) Comparison of the width of the vulnerable window between WT and N588K in the MIDDLE region of the 1D strand marked by double lines.
