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. 2011 Dec 15;7(12):e1002414. doi: 10.1371/journal.pgen.1002414

Figure 7. The loop of the hairpin/cruciform structure is critical for DGR function.

Figure 7

(A) Substitution mutations or insertions in loop sequences are shown. Boxed TAG, mtd stop codon. (B) Both the loop sequence and size are highly critical for DGR mutagenic homing. PCR-homing assays are shown along with primers used. (C) Effects of loop modifications on phage tropism switching frequencies. The bars represent mean TSF ± s.d. P values comparing mutants to WT in Student's t tests are indicated with asterisks. *P<0.05.