Table 1. Regions showing strongest evidence of recent positive selection in the European component.
Cytological Position | Genes (Number) | Size(kb) | Number of SNPs with |iHS|>2.5 | Max |iHS| |
6p21.33-32 | TRIM31, HLA (88) | 2000 | 113/581 | 5.71 |
15q11-q12 | APBA2 (1) | 194 | 30/37 | 4.41 |
17q24 | RGS9 (1) | 268 | 33/54 | 4.36 |
18p11.23 | PTPRM (1) | 192 | 24/34 | 4.31 |
15q26.1 | none | 154 | 20/50 | 4.02 |
5q22.1 | TMEM232, SLC25A46 (2) | 309 | 19/26 | 4.00 |
9p22.3 | SMARCA2 (1) | 87 | 29/47 | 3.95 |
3q22.1 | COL6A5 (1) | 164 | 17/36 | 3.89 |
9q33.2 | DENND1A (1) | 480 | 34/61 | 3.86 |
3p14.1 | none | 82 | 13/23 | 3.84 |
22q12.2 | SFI1, PISD (3) | 267 | 17/31 | 3.83 |
Gene (Number) displays the number of genes in the region; in the case a region encompasses multiple genes, we arbitrarily choose two. Size denotes the length of the region under selection; consecutive regions are merged. Number of SNPs with |iHS|>2.5 provides the number of SNPs with |iHS|>2.5 / total number of SNPs. Max |iHS| is the maximum |iHS| score achieved in a region.