Figure 7. TCDD-induced blood flow defects are reduced in dnAhr2^1–440-transgenic zebrafish.

Transgenic and wild type AB zebrafish were exposed to TCDD immediately following fertilization, and at 96 hpf caudal blood flow was scored for each fish. Scores were: 3, no flow; 2, clearly diminished flow; 1 slightly diminished flow; 0 normal flow. The bars indicate the distribution across each of the severity categories: Dark bars indicate dnAhr2^1–440-transgenics; light bars indicate wild type. Representative photographs illustrate each edema severity score. Asterisk indicates a significant difference between the transgenic and wild type percentage for that severity category, p<0.05.