Table 3. Differentially expressed loci in anti-sense direction, ranked by locus number, between N. meningitidis H44/76 wild type and N. meningitidis H44/76ΔmseR.
reads/locusα | ||||||
Locusβ | Geneγ | wt | ΔmseR | Fold change | p-valueδ | Descriptionε |
NMH_0763 | nqrE | 30 | 121 | 4.0 | 0.020 | NADH: ubiquinone oxidoreductase |
NMH_2154 | 157 | 19 | 0.1 | <0.001 | Hypothetical protein in σE operon | |
NMH_2156 | σE | 26 | 141 | 5.4 | 0.001 | RNA polymerase σE, σE operon |
NMH_2475 | 17 | 461 | 27.1 | <0.001 | mechanosensitive ion channel family protein | |
NMH_2476 | 6 | 725 | 120.8 | <0.0001 | Competence/damage-inducible CinA C-terminal | |
NMH_2477 | msrA/msrB | 771 | 118 | 0.2 | <0.0001 | methionine sulfoxide reductase msrA/msrB |
Reads/locus after library normalization by DEseq.
Locus number as annotated in H44/76 WGS (AEQZ00000000).
Gene name when annotated in H44/76 WGS (AEQZ00000000).
All loci with Benjamini-Hochberg adjusted p-value≤0.05.
Where available N. meningitidis strain MC58 orthologues are noted.