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. 2011 Dec 15;6(12):e29241. doi: 10.1371/journal.pone.0029241

Figure 3. Pathway analysis of genes with steady-state response to repeated small UVB perturbations created using PathwayAssist.

Figure 3

A) Up-regulated genes are primarily associated with the functions of anti-proliferation, anti-mitogenesis, and apoptosis. B) Down-regulated genes are mainly related to the functions of proliferation, mitogenesis, and anti-apoptosis. The plus and the minus symbols mark positive and negative regulations, respectively. Yellow boxes mark biological functions. Purple circles mark genes teased out by the steady-state model-fitting algorithm. Genes without data connection in the PathwayAssist database are pictured on the left without connection.