Table I.

C5a receptors selected for modeling (the data adopted from Ref. ¹ and Ref. ²)

Receptors were co-expressed in BY1142 yeast with and without the C5a ligand. Receptor signaling strength was measured by the ability of yeast to grow in the absence of histidine and at the various concentrations of 3-aminotriazole (AT) ²⁷: ++++++, growth on 50 mM AT; +++++, on 20 mM AT; ++++, on 10 mM AT; +++, on 5 mM AT.