. Author manuscript; available in PMC: 2013 Jan 1.

Published in final edited form as: Proteins. 2011 Sep 30;80(1):71–80. doi: 10.1002/prot.23162

Table III.

Contacts between the side chains of EC3 and other residues of the EC1+EC2+EC3+TM constructs in the structures of the CAM (top half) and non-CAM clusters (bottom half). Occurrences of hydrogen bonding are shown in bold.

Receptor	Residues of EC3

	L268	E269	P270	S271	S272	P273	T274	F275	L276	L277	L278	N279	K280
R25		R200	M265			Y181			Y258			F190
			R200			Y192			M265
						F193
R17		F181	R200		K185	K185	K185				M264	L187
		R200	M265			L187						S283
						V190
						Y192
R115	R200	M264									D191	S283
		F267									M265
											L281
R111	F267	E195	L194			R178	Y192		L194		M264	V190
			E195			P183			R200		M265	S283
						L194			M265		L281
R127		R200	R197				K191		Y192		T261	S283
			R200						R200		M265
											L281
R125	F267	M265	M265				H194	E191	L187			V190
								R200	E191			D282
								M265				S283
R128		T193	D191			A189				M264	V190
		R200	T193			H194				L281	D191
			R200								T261
			M265								M265

WT		M264	F267					K185		L281	T261	L187
WT		F267						L187			M265	S283
R12	Y192	M264	F267					M264		V189	M264	V189
		F267						L281		D191	M265	S283
											L281
R6	R200	M264	M264					K185		M264	M264	Q187
R6			F267									S283
R27	H194	F267					M264	M265			M264	V186	V186
											L281		V187
													S283
R20		M264	F267					M264			T261	K185	S283
		F267						L281			M264	L187
											M265	S189
											L281