Table 4.
Predicted consequences for deaminated methyl-CpGs in AARS exon 8
| CpGa | Affected Amino Acid | Predicted Change |
|---|---|---|
| 1b | R326 | W |
| 1c | R326 | Q |
| 2b | R329 | C |
| 2c | R329 | H |
| 3b | R330 | * |
| 3c | R330 | Q |
| 4b | R333 | * |
| 4c | R333 | Q |
| 5c | A335 | T |
| 6b | T348 | M |
| 7c | V354 | I |
Numbers refer to the annotations presented in Figure 3E.
CpG on coding strand
CpG on non-coding strand