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Effects of LSD1 inhibitors and DNMT inhibitor and/or HDAC inhibitor on ERα expression. MDA-MB-231 cells were treated with LSD1inhibitor 2d (A) or PG11144 (B) alone or with DNMT inhibitor (Aza) and/or HDAC inhibitor (MS275) for 24 h. Total RNA was extracted and cDNA was synthesized. The qRT-PCR was used to measure the gene expression. GAPDH expression was used as an internal control. The results are the mean ± S.E. of three independent experiments performed in triplicate.
