Fig. 4.
ODC enzyme activity was assayed in H157 SCR (SCR 4, SCR 8) or AZKD (AZ 9, AZ 11) clones. Cells were untreated (open bars), treated with 2.5 μM BENSpm (gray bars), or treated with 10 μM spermine with 1 mM aminoguanidine (black bars) for 24 h. Results shown are the mean and SEM of three independent experiments with four replicates per experiment. 1Denotes statistical significance between treated and control cells. 2Denotes statistical significance (p<0.05) between AZKD and SCR clones.