Table 4.
AUC values and percentage of the ranked compounds necessary to fine 25% and 50% of the actives, yielded by BSP-SLIM and DOCK6. The average values are also depicted in the table
AUC
|
% of db to find 25% of actives
|
% of db to find 50% of actives
|
||||
---|---|---|---|---|---|---|
BSP-SLIM | DOCK6 | BSP-SLIM | DOCK6 | BSP-SLIM | DOCK6 | |
CDK2 | 0.59 | 0.35 | 16.4 | 54.7 | 34.5 | 72.4 |
EGFr | 0.81 | 0.39 | 4.2 | 32.6 | 14.5 | 79.9 |
FGFr1 | 0.68 | 0.49 | 10.8 | 14.3 | 18.3 | 58.2 |
PDE5 | 0.89 | 0.57 | 1.9 | 13.6 | 7.1 | 44.3 |
Thrombin | 0.66 | 0.66 | 21.6 | 3.1 | 27.0 | 19.6 |
TK | 0.95 | 0.47 | 0.5 | 38.0 | 0.8 | 58.5 |
| ||||||
Avg. | 0.76 | 0.49 | 9.2 | 26.1 | 17.0 | 55.5 |