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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Cell Microbiol. 2011 Sep 28;14(1):28–39. doi: 10.1111/j.1462-5822.2011.01694.x

Fig. 1. Natural infection with mutant Salmonella SL3201 (avrA−) induces a more severe inflammatory response.

Fig. 1

A. H & E staining of cecal mucosa sections from mice at 24 hours following oral infection with the indicated Salmonella genotypes. Scale bar: 50μm. Arrow: goblet cells.

B. Semi-quantitative inflammatory scores of murine cecal mucosa from H & E staining of sections 24 h p.i. displayed in A. Edema, infiltration of polymorphonuclear cell, decrease of goblet cell numbers, and integrity of epithelial layer were scored separately.

C. Cecum MPO (myeloperoxidase) activity in mice orally infected with the indicated Salmonella geneotypes at 6, 12, 24, or 48 hours p.i.. Error bars represent Standard Error (n=5). Data were analyzed first using Two way ANOVA, then Bonferroni post test (* P<0.05, ** P<0.01, *** P<0.001).