Figure 2.

Receiver Operating Characteristic curves for the eight logistic regression models on two independent validation data sets. The KE data set was paired drug data from AERS, not used in training, where at least one of the drugs of the pair is known to be associated with the adverse event (according to FDA drug labels). The second validation data set (VA) was a list of critical and significant DDIs from the Veterans Affairs Hospital in Arizona provided by Olvey, et al CHOL, Cholesterol; DEPR, Depression; DIAB, Diabetes; HEPTOX, Hepatotoxicity; HTN, Hypertension; LIVDYS, Liver Dysfunction; RENIMP, renal impairment; SUIC, Suicide.