Table 2.
Subsets of angiogenic genes associated with LV function.
| Cluster | Protein number | Interaction number | MCODE score* | Genes |
|---|---|---|---|---|
| 1 | 3 | 4 | 1 | TGFBR1, TGFBR2, CLU |
| 2 | 5 | 7 | 1 | TGFBR1, TGFBR2, CLU, MAP3K7, FOS |
| 3 | 10 | 16 | 1.3 | TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1 |
| 4 | 12 | 20 | 1.42 | TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, |
| 5 | 13 | 22 | 1.38 | TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2 |
| 6 | 16 | 27 | 1.37 | TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2, FYN, LCK, CD55 |
| 7 | 21 | 34 | 1.38 | TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2, FYN, LCK, CD55, ATP5B, SRC, MYOC, ANXA2, PLG |
| 8 | 28 | 44 | 1.32 | TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2, FYN, LCK, CD55, ATP5B, SRC, MYOC, ANXA2, PLG, SOD1, BCL2, MAPK14, SMAD7, SHC1, MME, ADM |
| 9 | 35 | 55 | 1.34 | TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2, FYN, LCK, CD55, ATP5B, SRC, MYOC, ANXA2, PLG, SOD1, BCL2, MAPK14, SMAD7, SHC1, MME, ADM, CFH, THBS1, KNG1, PLAUR, PRKCA, RAB25 |
*MCODE cluster score = density * number of nodes.