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. 2011 Sep 12;589(Pt 22):5517–5528. doi: 10.1113/jphysiol.2011.216341

Table 2.

Muscle metabolic responses (means ± SD) during high-intensity exercise in normoxic control and in hypoxia after placebo (H-PL) and nitrate supplementation (H-BR)

H-PL H-BR CON
[PCr] (mm)
 Baseline 33.1 ± 2.8 30.6 ± 3.9 31.2 ± 2.8
 Δ 60 s −13.2 ± 2.7 −11.1 ± 2.9* −11.4 ± 2.7*
 Δ 120 s −16.6 ± 2.2 −14.1 ± 3.0* −15.1 ± 3.1
 Δ 180 s −18.4 ± 2.4 −16.1 ± 3.2* −17.3 ± 3.3
 At task failure 12.0 ± 3.6 11.3 ± 3.3 12.1 ± 2.4
 Δ (μm s−1) −63 ± 28 −48 ± 21* −48 ± 24*
[Pi] (mm)
 Baseline 3.3 ± 0.7 3.1 ± 0.7 3.2 ± 0.9
 Δ 60 s 10.4 ± 2.5 8.5 ± 2.1* 8.5 ± 2.5*
 Δ 120 s 15.0 ± 3.3 12.2 ± 3.0* 11.7 ± 3.9*
 Δ 180 s 17.1 ± 4.4 13.8 ± 4.3* 13.4 ± 4.0*
 At task failure 21.4 ± 4.7 19.1 ± 5.4 18.3 ± 3.3
 Δ (μM s−1) 54 ± 26 40 ± 21* 39 ± 24*
[ADP] (μM)
 Baseline 7.6 ± 1.1 6.9 ± 1.6 7.2 ± 1.4
 Δ 60 s 48.1 ± 17.4 33.6 ± 11.3* 34.4 ± 13.0*
 Δ 120 s 59.7 ± 18.5 44.0 ± 13.6* 46.7 ± 15.0
 At task failure 102.9 ± 58.6 84.2 ± 28.6 75.5 ± 19.9
 Δ (nm s−1) 286 ± 177 191 ± 104 177 ± 107
pH
 Baseline 7.03 ± 0.03 7.02 ± 0.03 7.01 ± 0.03
 At task failure 6.85 ± 0.07 6.89 ± 0.07 6.88 ± 0.08
 Rate of change (ks−1) −0.52 ± 0.24 −0.34 ± 0.30* −0.32 ± 0.29*

Note that there were no significant differences in any of the variables between H-BR and CON. Amplitude indicates the change from baseline to task failure. ks, kiloseconds.

*

Different from H-PL, P < 0.05.